Warning: array_key_exists(): The first argument should be either a string or an integer in D:\Inetpub\webs\924517_web\www\lang_set.inc.php on line 7 Prof. MUDr. Cyril Höschl DrSc. FRCPsych.

Journal publications in English

Previous | 1 | 2  Move down


  1. Bares M, Novak T, Kopecek M, Stopkova P, Cermak J, Kozeny J, Höschl C. Antidepressant combinations and monotherapy in the treatment of resistant depression: a randomised, open-label study. Int J Psychiatry Clin Pract. 2012 Apr 10. [Epub ahead of print]
  2. Hajek T, Kopecek M, Höschl C, Alda M. Smaller hippocampal volumes in patients with bipolar disorder are masked by exposure to lithium: a meta-analysis. J Psychiatry Neurosci, 37; 2012, 3:1-11.
  3. Mohr P, Höschl C, Volavka J. Teaching critical appraisal of articles on psychopharmacology. Acad Psychiatry. 2012 Mar 1;36(2):114-7.
  4. Hajek T, Cullis J, Novak T, Kopecek M, Höschl C, Blagdon R, O'Donovan C, Bauer M, Young LT, Macqueen G, Alda M. Hippocampal volumes in bipolar disorders: opposing effects of illness burden and lithium treatment. Bipolar Disord. 2012 May;14(3):261-270.
  5. Páleníček T, Fujáková M, Brunovský M, Horáček J, Gorman I, Balíková M, Rambousek L, Syslová K, Kačer P, Zach P, Bubeníková-Valešová V, Tylš F, Kubešová A, Puskarčíková J, Höschl C. Behavioral, neurochemical and pharmaco-EEG profiles of the psychedelic drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in rats. Psychopharmacology (Berl).2013; 225(1):75-93
  6. Spaniel F, Hrdlička J, Novák T, Kožený J, Höschl C, Mohr P, Motlová LB. Effectiveness of the Information Technology-Aided Program of Relapse Prevention in Schizophrenia (ITAREPS): A Randomized, Controlled, Double-Blind Study. J Psychiatr Pract. 2012 Jul;18(4):269-80.
  7. Höschl C, Winkler P, Pěč O. The state of psychiatry in the Czech Republic. Int Rev Psychiatry. 2012 Aug;24(4):278-85.
  8. Klirova M, Horacek J, Novak T, Cermak J, Spaniel F, Skrdlantova L, Mohr P, Höschl C. Individualized rTMS neuronavigated according to regional brain metabolism ([18]FGD PET) has better treatment effects on auditory hallucinations than standard positioning of rTMS: a double-blind, sham-controlled study. Eur Arch Psychiatry Clin Neurosci. 2012 Sep 15. [Epub ahead of print]
  9. Holub D, Flegr J, Dragomirecká E, Rodriguez M, Preiss M, Novák T, Čermák J, Horáček J, Kodym P, Libiger J, Höschl C, Motlová LB. Differences in onset of disease and severity of psychopathology between toxoplasmosis-related and toxoplasmosis-unrelated schizophrenia. Acta Psychiatr Scand. 2012 Nov 5. doi: 10.1111/acps.12031. [Epub ahead of print]
  10. Hajek T, Cullis J, Novak T, Kopecek M, Blagdon R, Propper L, Stopkova P, Duffy A, Hoschl C, Uher R, Paus T, Young LT, Alda M. Brain structural signature of familial predisposition for bipolar disorder: replicable evidence for involvement of the right inferior frontal gyrus. Biol Psychiatry. 2013 Jan 15;73(2):144-152
  11. Hajek T, Kopecek M, Alda M, Uher R, Höschl C. Why negative meta-analyses may be false? Eur Neuropsychopharmacol. 2013 Feb 9. pii: S0924-977X(13)00039-4. doi: 10.1016/j.euroneuro.2013.01.004. [Epub ahead of print]
  12. Fountoulakis KN, Hoschl C, Kasper S, Lopez-Ibor J, Möller HJ. The media and intellectuals' response to medical publications: the antidepressants' case. Ann Gen Psychiatry. 2013 Apr 12;12(1):11.
  13. Bauer M et al.; World Federation of Societies of Biological Psychiatry. Task Force on Unipolar Depressive Disorders. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders, part 1: update 2013 on the acute and continuation treatment of unipolar depressive disorders. World J Biol Psychiatry. 2013 Jul;14(5):334-85. doi: 10.
  14. Kožený J., Tišanská L., Höschl C.: Assessing empathy among Czech medical students: a cross-sectional study. Československá psychologie, 57; 2013, 3:246-254.
  15. Bares M, Brunovsky M, Novak T, Kopecek M,Stopkova P, Sos P,Höschl C. QEEG Theta Cordance in the Prediction of Treatment Outcome to Prefrontal Repetitive Transcranial Magnetic Stimulation or Venlafaxine ER in Patients With Major Depressive Disorder. Clinical EEG and Neuroscience, 2015, Vol. 46(2): 73–80
  16. Brunovský M, Horáček J, Nová T, Klírová M, Kohútová B, Krajča V, Höschl C. Modulating cortical connectivity in schizophrenic patients with auditory hallucinations by rTMS assessed with exact low-resolution brain tomography (eLORETA). Clinical Neurophysiology, 125,2014;5:e39–e40
  17. Stein DJ, Ahokas A, Márquez MS, Höschl C, Oh KS, Jarema M, Avedisova AS, Albarran C, Olivier V. Agomelatine in generalized anxiety disorder: an active comparator and placebo-controlled study. J Clin Psychiatry. 2014 Apr;75(4):362-368. doi: 10.4088/JCP.13m08433.
  18. Bares M, Novak T, Kopecek M, Brunovsky M, Stopkova P, Höschl C. The effectiveness of prefrontal theta cordance and early reduction of depressive symptoms in the prediction of antidepressant treatment outcome in patients with resistant depression: analysis of naturalistic data. Eur Arch Psychiatry Clin Neurosci (2015) 265:73–82
  19. Fountoulakis KN, Kawohl W, Theodorakis PN, Kerkhof AJFM, Navickas A, Höschl C, et al. Relationship of suicide rates to economic variables in Europe: 2000-2011. BJPsych, published online October 30, 2014 at DOI: 10.1192/bjp.bp.114.147454
  20. Horacek J, Mikolas P, Tintera J, Novak T, Palenicek T, Brunovsky M, Höschl C, Alda M. Sad mood induction has an opposite effect on amygdala response to emotional stimuli in euthymic patients with bipolar disorder and healthy controls. J Psychiatry Neurosci. 2015 Mar;40(2):134-42.
  21. Melicher T, Horacek J, Hlinka J, Spaniel F, Tintera J, Ibrahim I, Mikolas P, Novak T, Mohr P, Hoschl C. White matter changes in first episode psychosis and their relation to the size of sample studied: A DTI study. Schizophrenia Research 2015 Mar;162(1-3):22-28
  22. Höschl C, Kane J, Gaebel W, Gorwood P, and Kennedy S. Hot Debates in CNS Disorders: Is Cognitive Impairment in Mental Disorders an Endophenotype or an Epiphenomenon? The Institute Magazine (ISSN: 1603-2683), 19; Feb 2015: 4-16
  23. Bhugra D, Ventriglio A, Kuzman MR, Ikkos G, Hermans MH, Falkai P, Fiorillo A, Musalek M, Hoschl C, Dales J, Beezhold J, Rössler W, Racetovic G, Gaebel W. EPA guidance on the role and responsibilities of psychiatrists. Eur Psychiatry. 2015 Mar;30(3):417-422.
  24. Hajek T, Cooke C, Kopecek M, Novak T, Hoschl C, Alda M. Using structural MRI to identify individuals at genetic risk for bipolar disorders: a 2-cohort, machine learning study. J Psychiatry Neurosci. 2015 Apr 8;40(2):140-142.
  25. Winkler P, Mladá K, Csémy L, Nechanská B, Höschl C. Suicides following inpatient psychiatric hospitalization: A nationwide case control study. J Affect Disord. 2015 Jun 10;184:164-169. doi: 10.1016/j.jad.2015.05.039. [Epub ahead of print]
  26. Spaniel F, Novak T, Bankovska Motlova L, Capkova J, Slovakova A, Trancik P, Matejka M, Höschl C. Psychiatrist's adherence: a new factor in relapse prevention of schizophrenia. A randomized controlled study on relapse control through telemedicine system. J Psychiatr Ment Health Nurs. 2015 Dec;22(10):811-820. doi: 10.1111/jpm.12251. [Epub ahead of print] PubMed PMID: 26176646.
  27. Spaniel F, Tintera J, Rydlo J, Ibrahim I, Kasparek T, Horacek J, Zaytseva Y, Matejka M, Fialova M, Slovakova A, Mikolas P, Melicher T, Görnerova N, Höschl C, Hajek T. Altered Neural Correlate of the Self-Agency Experience in First-Episode Schizophrenia-Spectrum Patients: An fMRI Study. Schizophrenia Bulletin, Dec 2015, doi:10.1093/schbul/sbv188
  28. Winkler P, Mladá P, Krupchanka D, Agius M, Ray MK, Höschl C. Long-term hospitalizations for schizophrenia in the Czech Republic 1998–2012. Schizophrenia Research, 175, August 2016; 1–3:180-185. DOI: http://dx.doi.org/10.1016/j.schres.2016.04.008
  29. Spaniel F, Bakstein E, Anyz J, Hlinka J, Sieger T, Hrdlicka J, Görnerová N, Höschl C. Relapse in schizophrenia: definitively not a bolt from the blue. Neurosci Letters. 2018; 669:68-74.
  30. Winkler P, Barrett B, McCrone P, Csémy L, Janous̆ková M, Höschl C. Deinstitutionalised patients, homelessness and imprisonment: systematic review. Brit J Psychiatry, May 2016, 208 (5): 421-428; DOI: 10.1192/bjp.bp.114.161943
  31. Zalsman G, Hawton K, Wasserman D, van Heeringen K, Arensman E, Sarchiapone M, Carli V, Höschl C, Barzilay R, Balazs J, Purebl G, Kahn JP, Sáiz PA, Lipsicas CB, Bobes J, Cozman D, Hegerl U, Zohar J. Suicide prevention strategies revisited: 10-year systematic review. The Lancet Psychiatry, Published online June 8, 2016
  32. Fountoulakis KN, Chatzikosta I, Pastiadis K, Zanis P, Kawohl W, Kerkhof AJFM, Navickas A, Höschl C, et al. Relationship of suicide rates with climate and economic variables in Europe during 2000–2012. Ann Gen Psychiatry (2016) 15:19. DOI 10.1186/s12991-016-0106-2
  33. Bares M, Novak T, Brunovsky M, Kopecek M, Höschl C. The Comparison of Effectiveness of Various Potential Predictors of Response to Treatment With SSRIs in Patients With Depressive Disorder. J Nerv Ment Dis. 2017 Aug;205(8):618-626. doi: 10.1097/NMD.0000000000000574.
  34. Winkler P, Krupchanka D, Roberts T, Kondratova L, Machů V, Höschl C, Sartorius N, et al. A blind spot on the global mental health map: a scoping review of 25 years' development of mental health care for people with severe mental illnesses in central and eastern Europe. The Lancet Psychiatry. 2017 Aug; 4(8):634-642.
  35. Krzak AM, Cao JJL, Agius M, Hoschl C. Does neurogenesis relate to depression and do antidepressants affect neurogenesis? Psychiatr Danub. 2017 Sep;29(Suppl 3):241-246.
  36. Mutlu O, Páleníček T, Pinterová N, Šíchová K, Horáček J, Holubová K, Höschl C, Stuchlík A, Erden F, Valeš K. Effects of the adipokinetic hormone/red pigment-concentrating hormone (AKH/RPCH) family of peptides on MK-801-induced schizophrenia models. Fundam Clin Pharmacol. 2018;32, 6:589-602
  37. Lehmann I., Chisholm D., Hinkov H., Höschl C., Kapócs G., Kurimay T., Lecic-Tosevski D., Nakov V., Réthelyi J.M., Winkler P., Zielasek J. & Gaebel W. DEVELOPMENT OF QUALITY INDICATORS FOR MENTAL HEALTHCARE IN THE DANUBE REGION. Psychiatria Danubina, 2018; Vol. 30, No. 2, pp 197-206.
  38. van Erp TGM, …, Hoschl C, …, Spaniel F, …, Turner JA. Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biological Psychiatry, in press, available online on May 18, 2018. https://doi.org/10.1016/j.biopsych.2018.04.023
  39. Stein DJ, Khoob J-P, Ahokas A, Jarema M, Van Ameringen M, Vavrusova L, Hӧschl C et al. 12-week double-blind randomized multicenter study of efficacy and safety of agomelatine (25–50 mg/day) versus escitalopram (10–20 mg/day) in out-patients with severe generalized anxiety disorder. Eur Neuropsychopharmacol, 28, 2018; 8: 970-979
  40. Kožený J, Tišanská L, Bednařík J, Höschl C. A Rasch analysis of the Q-LES-Q-SF questionnaire in a cohort of patients with neuropathic pain. Cesk Slov Neurol N 2019; 82/115(1): 60–67
  41. Fountoulakis KN, ..., Spaniel F, Knytl P, Furstova P,..., Hoschl C. et al. Staging of Schizophrenia With the Use of PANSS: An International Multi-Center Study. Int J Neuropsychopharmacology (2019) 22(11): 681–697
  42. Wong YT, Radua J, Pomarol-Clotet E, ..., Skoch A, Spaniel F, Hoschl C. et al.: An overlapping pattern of cerebral cortical thinning is associated with both positive symptoms and aggression in schizophrenia via the ENIGMA consortium. Psychological Medicine. 2020, 50(12),2034-2045. ISSN 0033-2917. 1–12. https://doi.org/10.1017/S0033291719002149. IF 5.813.
  43. Kútna V, Uttl L, Waltereit R, Krištofiková Z, Kaping D, Petrásek T, Hoschl C, Ovsepian SV. Tuberous Sclerosis (tsc2+/-) Model Eker Rats Reveals Extensive Neuronal Loss with Microglial Invasion and Vascular Remodeling Related to Brain Neoplasia. Neurotherapeutics. 2020 Jan;17(1):329-339. doi: 10.1007/s13311-019-00812-6
  44. Fountoulakis KN,..., Spaniel F, Knytl P, Furstova P,..., Hoschl C,..., Kasper S, De Hert M (2020). Modeling psychological function in patients with schizophrenia with the PANSS: an international multi-center study. CNS Spectrums, 1-9. https://doi.org/10.1017/S1092852920001091
  45. Gaebel W, Lehmann I, Chisholm D, Hinkov H, Höschl C, Kapócs G, Kurimay T, Lecic Tosevski D, Milosavljevic M, Nakov V, Winkler P, Zielasek J. Quality indicators for mental healthcare in the Danube region: results from a pilot feasibility study. Eur Arch Psychiatry Clin Neurosci (2020). https://doi.org/10.1007/s00406-020-01124-z
  46. Hromadkova L, Bezdekova D, Pala J, Schedin-Weiss S, Tjernberg LO, Hoschl C, Ovsepian SV. Brain-derived neurotropic factor (BDNF) promotes molecular polarization and differentiation of immature Neuroblastoma cells into definitive neurons. BBA - Molecular Cell Research 1867 (2020) 118737, DOI: 10.1016/j.bbamcr.2020.118737
  47. Holleran L, Kelly S , …, Hoschl C, …, Spaniel F, Stein DJ et al. The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium. Am J Psychiatry, 177, 2020; 6: 537-547
  48. Ovsepian SV, Horacek J, O’Leary VB, Hoschl C: The Ups and Downs of BACE1: Walking a Fine Line between Neurocognitive and Other Psychiatric Symptoms of Alzheimer’s Disease. The Neuroscientist, 2021 Jun;27(3):222-234. doi: 10.1177/1073858420940943. Epub 2020 Jul 25.
  49. Radua J, Vieta E, Shinohara R, …, Hoschl C, …, Turner J, van Erp T, ENIGMA Consortium collaborators. Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA. NeuroImage, Vol. 218, Sept. 2020, 116956. https://doi.org/10.1016/j.neuroimage.2020.116956
  50. Mutlu O, Kurtas O, Kleteckova L, Pinterova N, Holubová K, Horacek J, Hoschl C, Uygun I, Rodriguez DB, Kacer D, Muhametaj F, Vales K. Effects of adipokinetic hormone/red pigment-concentrating hormone family of peptides in olfactory bulbectomy model and posttraumatic stress disorder model of rats. Peptides. 2020 Sep 18;134:170408. doi: 10.1016/j.peptides.2020.170408. Online ahead of print.PMID: 3295
  51. O’Leary VB, Dolly JO, Höschl C, Cerna M, Ovsepian SV: Unpacking Pandora from its Box: Deciphering the Molecular Basis of the SARS-CoV-2 Coronavirus. Int. J. Mol. Sci. 2021, 22, 386. https://doi.org/10.3390/ijms22010386
  52. Vrajová M, Šlamberová R, Hoschl C, Ovsepian SV. Methamphetamine and Sleep: Neurobehavioral Correlates and Molecular Mechanisms. Sleep, 6 Jan 2021. https://doi.org/10.1093/sleep/zsab001
  53. Kutna V, O'Leary VB, Newman E, Hoschl C, Ovsepian SV. Revisiting Brain Tuberous Sclerosis Complex in Rat and Human: Shared Molecular and Cellular Pathology Leads to Distinct Neurophysiological and Behavioral Phenotypes. NEUROTHERAPEUTICS. Early Access: JAN 2021; DOI: 10.1007/s13311-020-01000-7
  54. Ovsepian SV, O’Leary VB, Hoschl C, Zaborszky L. Integrated phylogeny of the human brain and pathobiology of Alzheimer’s disease: A unifying hypothesis. Neuroscience Letters 755 (2021) 135895. doi.org/10.1016/j.neulet.2021.135895
  55. Ovsepian SV, O’Leary VB, Hoschl C. Mainstream psychiatry reinstates therapeutic ventures of the remote past. Drug Discovery Today, Vol 26, 2021; 3:845-851
  56. Jorratt P, Hoschl C, Ovsepian SV. Endogenous antagonists of N-methyl-D-aspartate receptor in schizophrenia. Alzheimer’s Dement. 2020;1–18. DOI: 10.1002/alz.12244
  57. Patel Y, Parker N, Shin Jean,...Höschl C, et al. Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders. JAMA PSYCHIATRY, Vol.78, 2021; 1:‏47-63
  58. Granak S, Hoschl C & Ovsepian SV. Dendritic spine remodeling and plasticity under general anesthesia. Brain Struct Funct (2021). https://doi.org/10.1007/s00429-021-02308-6
  59. Fountoulakis K, Dragioti E, (…) Spaniel F, Knytl P, Furstova P,(…) Hoschl C, (…) De Hert M: Modeling psychological function in patients with schizophrenia with the PANSS: an international multi-center study. CNS Spectrums, Volume 26, Issue 3, June 2021, pp. 290 - 298
  60. Kútna V, O'Leary VB, Höschl C, Ovsepian SV. Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism-like neurobehavioral phenotype in a rat model. Autism Research, 15(5), 791–805. https://doi.org/10.1002/ aur.2688
  61. Fountoulakis KN, Dragioti E, …, Spaniel F, Knytl P, Furstova P,…, Höschl C,…, De Hert M. (2021). Gender, age at onset, and duration of being ill as predictors for the long-term course and outcome of schizophrenia: An international multicenter study. CNS Spectrums, 1-8. doi:10.1017/S1092852921000742
  62. Georgiadis F, Larivière C, Glahn D, ..., Hoschl C, Spaniel F, ..., van Erp T.G.M., Turner J, Bernhardt B, Kirschner M. Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study. Preprint, doi: https://doi.org/10.1101/2023.02.12.527904.
  63. Georgiadis, F., Larivière, S., Glahn, D.,…Höschl C,…, et al. Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study. Mol Psychiatry (2024)

Previous | 1 | 2  Move up